Police seized around £170,000-worth of drugs from a car in Douglas this morning.
Officers say two women from Liverpool, aged 24 and 27, were detained at a hotel in Douglas at around 6.30am and their vehicle searched.
Approximately £108,000-worth of cannabis resin, and £62,000-worth of what's thought to be cocaine, was found.
The women are currently at police headquarters, helping officers with their inquiries.
Isle of Man faces renewed scrutiny ahead of Moneyval inspection
Concerns raised over anti-money laundering effectiveness as international assessment approaches
Mobile classroom proposed for UCM horticulture compound
Application aims to reduce disruption and improve access for practical lessons
Chance to learn more about career opportunities on Island
Registration open for young adult and graduate fair
Report highlights risks of environmental crime entering financial system
Financial Intelligence Unit urges greater awareness after survey finds low preparedness across regulated sector
Peel secondary school to carry out lockdown drill next week
QEII High School says exercise is part of routine emergency planning and reassures parents no threat is anticipated