It should be open again by 2.30pm
The entire Mountain Road is currently closed, from Ramsey to the Creg-Ny-Baa.
The emergency closure is to allow for the road to be swept following a diesel spillage along its entire length.
The Department of Infrastructure says it should be open again by 2.30pm.
Emergency access will be maintained throughout the period of the closure.
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It's due to start at 00.30am until 3.30am on Wednesday (30 September)