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People sending mail to London are being warned to expect disruptions on Friday, when Royal Mail workers are due to stage a 24-hour strike.
The industrial action is expected to delay the delivery of most items posted to the capital on Thursday and Friday.
Any post sent from London to the Isle of Man on Friday will also be delayed.
Isle of Man Medical Society welcomes health review, saying it's 'time to listen to doctors'
MIAA finds health and care model 'not operating as well as originally intended'
MHK: Minister should resign if he disagrees with minimum wage policy
Lawrie Hooper says it's 'laughable' that Treasury feels bound by Tynwald vote
Manx farmer 'delighted' but aware 'far from out of the woods'
On Friday, Milan Veterinary Practice announced it will continue farm services from 1 December.
Charity appealing for public to donate toys
Salvation Army received almost 500 gifts last year
Chance to see the Leonid meteor shower tonight
It will be seen from the Northern and Southern hemispheres