Roadworks which were suspended for the Christmas and New Year period will resume from Monday.
The reconstruction of the Minorca Crossroads on the Ramsey Road in Laxey will continue, with 24 hour traffic signals and the closure of side roads.
The White Hoe to Old Castletown Road will be affected by some footway work, as will the stretch between the Ballafletcher Roundabout and Noble's Hospital.
The DoT is also planning some tree felling work, which will involve the closure of Victoria Road, Douglas the following weekend, on Sunday, January 11.
There will be carriageway reconstruction work at Janet's Corner, Castletown which will put the King William's Road junction out of action, and there will be similar work at Saddle Road, Braddan.
Man treated for non-life threatening injuries following Ramsey incident
Two suspects in custody following Ramsey incident
Consultation open on plans to formally recognise the heritage of Douglas Head
Police dealing with 'serious incident' in Ramsey
Drop-in session to support Isle of Man charities