Roadworks which were suspended for the Christmas and New Year period will resume from Monday.
The reconstruction of the Minorca Crossroads on the Ramsey Road in Laxey will continue, with 24 hour traffic signals and the closure of side roads.
The White Hoe to Old Castletown Road will be affected by some footway work, as will the stretch between the Ballafletcher Roundabout and Noble's Hospital.
The DoT is also planning some tree felling work, which will involve the closure of Victoria Road, Douglas the following weekend, on Sunday, January 11.
There will be carriageway reconstruction work at Janet's Corner, Castletown which will put the King William's Road junction out of action, and there will be similar work at Saddle Road, Braddan.
MHKs explain their 'no vote' decision in chief minister election
Farmers union declares no faith in DEFA leadership
Major incident declared as crews battled fire
New 'rent-to-buy' option for first-time homeowners on the Isle of Man