Manx cyclist Jonny Bellis will be one of the first from the British team in action.
The 248 kilometre road race begins at 4 o'clock our time Saturday morning.
Former Olympic cyclist Marie Noon says the timing may mean Jonny missing today's Opening Ceremony:-
TT 2025: Dunlop does the Supersport double
Victory is his eighth successive TT win in the class
TT: Revised Friday racing schedule confirmed
Contingency day available tomorrow is not being utilised
TT 2025: Sidecar TT Race 2 postponed
No further racing today due to forecast poor weather
TT 2025: Thousands raised to help Founds & Walmsley
Sidecar team aiming to raise vital funds after TT crash
TT 2025: Hankocyova 'stable, conscious and talking' after Supertwin incident
Rider came off at Douglas Road Corner during race last night (3 June)