Visit to winless Oswestry
In Rugby, South Lancashire and Cheshire Division One leaders Douglas will be out for a full five point haul from their visit to bottom-of-the-table Oswestry.
The home side have lost all eleven matches this season and have shipped an average of over 44 points a game.
In Division Two, Vagabonds are at home to Ruskin Park with a tight encounter expected at Ballafletcher.
And in Division Three, Ramsey have a vital trip to fellow promotion hunters Congleton - a win on the road here could prove vital at the end of the season.
Holden 'proud' of FC Isle of Man efforts this season
Rugby: Douglas head to Vale of Lune for play-off challenge
Hockey: IoM Women's Over-45's set for EH Championship semi-final
Football: 2026 Hospital Cup & Junior Cup competitions to get underway
'It's a great opportunity' Island cricketers speak on chance to represent European sides