Douglas lost out 23-11 to Whitehaven to end their RFU Vase hopes.
The visitors to Port-e-Chee are top of their Cumbria league and unbeaten so far this season.
Douglas took an early lead through two Bryn Snellgrove penalties but by half-time, tough tackling Whitehaven were in control 13-6.
A Mike Hebden try in the second half gave Douglas a glimmer of hope but, in the end, Whitehaven were just too strong.
Ravens 'champing at the bit' to respond against Charnock Richard
FC Isle of Man looking to bounce back from previous defeat
Hockey: New mixed season enters second week
Multiple sides hoping to build on good opening day results
TT 2027 race schedule announced
Senior race moved and one Superstock event axed in revised programme
Rugby: Douglas to host newly-promoted Wilmslow in season opener
Manx side begin latest Regional 2 North West campaign this weekend