Title contenders look for away success
The top three in the Canada Life Premier League all have away fixtures against sides near the bottom end of the table.
Corinthians are leaders on goal difference and make the short trip to Braddan.
In-form Peel are second and head north to Ramsey.
And champions St. George's are six points back in third but have three games in hand - they are away at Douglas Royal.
Elsewhere, St. John's travel to The Bowl to face St. Mary's.
Division Two leaders Pulrose have the chance to pull three points clear of rivals Castletown.
Castletown don't have a game while Pulrose make the trip to bottom team Governor's Athletic.