On verge of another Premier title
St. George's are closing in on being crowned Canada Life Premier League champions again.
They welcome Rushen to Glencrutchery Road looking for a 10th straight victory.
Rushen are third and have lost just once in the last eight matches.
Second placed St. Mary's need to get back to winning ways after a dip in form when they travel to Union Mills.
Corinthians should stretch their unbeaten run to eleven games when they visit bottom side and already relegated Ayre.
Elsewhere, Old Boys tackle Peel at Blackberry Lane, Douglas Athletic host Ramsey and Colby face St. John's.
Athletics: Big Island turnout expected at Manchester Marathon
Football: Colby stun defending champions in Hospital Cup
Rugby: Douglas beaten in Regional 2 North West play-offs
Spirited FC Isle of Man lose out at Padiham
Hockey: IoM Women's Over-45's set for EH Championship semi-final