A weakened Vagabonds side was comprehensively thrashed 55-3 by promotion favourites Widnes.
Vagas were still in touch at half-time, trailing 10-3 with their only points coming via a Jonny Beckley penalty.
However, Widnes turned on the style in the second half, running in eight unanswered tries to take the spoils.
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Vagabonds men and Douglas also take respective wins on home soil