Castletown head to Tromode
Cronkbourne will look for another win to close in on Cricket's Premiership title.
They are at home to fifth in the table Castletown at Tromode.
Leaders Cronkbourne are 21 points clear at the top and have a game in hand on their nearest rivals.
Second placed Peel and St. John's take the short trip to Crosby while Ramsey host the Isle of Man Cricket Association Development side.
All matches start at 1pm on Saturday.